Cervical Length in Cases of Placenta Previa

• Conditions: Placenta Previa

• Registration Number: NCT03451136
• Lead Sponsor: Cairo University

Brief Summary

This study establishes the relationship between cervical length and whether it can be used to predict haemorrhage and preterm delivery in cases of placenta previa.

Detailed Description

Some studies have reported an association between ultrasonographic decreased cervical length and the likelihood of complications as antepartum or post-partum haemorrhage requiring an emergency caesarean section (CS) .

The safety of trans-vaginal scanning is not in doubt, and the technique now has widespread acceptance. As a consequence, the clinical presentation of placenta previa has changed and most low lying placentas are diagnosed during the second trimester anomaly scan.

The objective of this study was to establish if there is a relation between transvaginal ultrasonographic measurement of cervical length in cases of placenta previa and whether it can be used as a predictor for antepartum haemorrhage or not.

Study Timeline

• Status Verified: 2018-02
• Study First Submitted: 2018-02-05
• Study First Submitted QC: 2018-02-28
• Last Update Submitted: 2018-02-28
• Study Start: 2018-03-01
• Study First Posted: 2018-03-01
• Last Update Posted: 2018-03-01
• Primary Completion: 2018-07-01
• Study Completion: 2018-07-15

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 80

Inclusion Criteria

1. Age: 20-45 years old
2. Single Pregnancy
3. Fetal gestational age 28 to < 36 weeks
4. Normal amniotic fluid index (AFI)
5. Diagnosis of placenta previa by pelvic ultrasound that was confirmed when the lower placental edge overlies the internal cervical os on transvaginal ultrasound (TVS).

Read More

Exclusion Criteria

1. Threatened preterm labor and maternal use of vaginal progesterone.
2. Preterm premature rupture of membranes;
3. Polyhydramnios;
4. Presence of cercelage and history of cervical cone biopsy which both affect cervical length.
5. Diagnosis of multiple fetal anomalies;
6. Women with other risk factors for intra-partum hemorrhage

Read More

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cervical length measured in mm in relation to antepartum haemorrhage	4 months	To find out the relationship between cervical length measured by transvaginal ultrasound and occurrence of antepartum hemorrhage in cases of placenta previa.

Secondary Outcome Measures

Name	Time	Method
Type of cesarean delivery	4 months	Elective or emergency cesarean delivery
Need for blood transfusion	4 months	Yes or no and no.of packed units
Need for caesarean hysterectomy	4 months	Yes or no
Need for neonatal ICU	4 months	Yes or no