Effects of selenium, vitamin C and N-acetylcysteine in the prevention of acute kidney injury after cardiac surgery
Phase 2
- Conditions
- Coronary Atrial Bypass Graft Pations.Atherosclerotic heart disease
- Registration Number
- IRCT2015021621098N1
- Lead Sponsor
- Vice Chancellor for Research, Mashhad University of Medical Science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 320
Inclusion Criteria
patient satisfaction; off-pump coronary artery bypass graft surgery method; there is no known history of renal including structural abnormalities; kidney failure or patients with a single kidney; non-emergency coronary artery bypass graft
Exclusion criteria: patients with chronic obstructive pulmonary disease; usage more than 2 units of blood during surgery; history of taking non-steroidal anti-inflammatory drugs; acute sepsis; patients with severe malnutrition; diabetes.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Acute kidney injury. Timepoint: Before intervention and every one hour after intervention until the end of Hospitalization. Method of measurement: Measurement of serum creatinine and urine output.
- Secondary Outcome Measures
Name Time Method Stay in ICU. Timepoint: Number of days of stay in ICU after surgery. Method of measurement: Day.