Comparison of the Effectiveness of Intravaginal Misoprostol with Extra-Amniotic Saline Infusion in Labor Inductio
- Conditions
- nfavorable cervix.
- Registration Number
- IRCT20201024049128N1
- Lead Sponsor
- Karaj University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 144
Singleton gestation
Alive fetus
Cephalic presentation
Intact membranes
Unfavorable cervix (Bishopscore =6)
Reassuring fetal heart rate
Gestational age=28
Non-cephalic presentation
Adequate uterine contractions (3 contractions Lasting for 30sec/10 min)
Ruptured membranes
Cephalopelvic disproportion
Multiple pregnancy
Polyhydramnios
Estimated fetal weight =4000g or =1800g
Placental abruption, Placenta previa
Unexplained vaginal bleeding
Prior lower segment cesarean section/Scarred uterus
Non-reassuring fetal status
Clinically detected vaginal infections(exp:genital herpes) or chorioamnionitis
Latex or Prostaglandins allergy or any contraindications receiving Prostaglandins, including a history of asthma, glaucoma, or cardiovascular disease
Intrauterine fetal death
Renal or hepatic failure
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The mean time interval from start of induction to delivery. Timepoint: Time of birth. Method of measurement: Clock.;Duration of latent phase. Timepoint: At the end of latent phase. Method of measurement: Clock.;Duration of active phase. Timepoint: At the end of active phase. Method of measurement: clock.;Rate of delivery within 12 hours. Timepoint: At the end of study. Method of measurement: Patient's file.;Rate of delivery within 24 hours. Timepoint: At the end of study. Method of measurement: Patient's file.
- Secondary Outcome Measures
Name Time Method Cesarean rate. Timepoint: At the end of study. Method of measurement: Patient's file.;Incidence of tachysystole. Timepoint: Continuously. Method of measurement: Cardiotocography.;Incidence of hypertonus. Timepoint: Continuously. Method of measurement: Cardiotocography.;Apgar score. Timepoint: 1 minute and 5 minutes after birth. Method of measurement: Examination of the newborn.;Incidence of meconium passage. Timepoint: At birth. Method of measurement: Examination of the newborn.;Incidence of chorioamnionitis. Timepoint: Every 3 hours. Method of measurement: Physical examination.