A Randomized Double Blind Comparative Study Of Ultrasound Guided Adductor Canal And Popliteal Block For Providing Anaesthesia To Below Knee Surgeries Using 0.5% Bupivacaine With Dexamethasone Versus 0.5% Bupivacaine With Dexmedetomidine.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- To assess, compare and evaluate the onset and duration of sensory and motor blockade, and duration of postoperative analgesia with hemodynamic parameters.
研究概览
简要总结
Peripheral nerve block provides anaesthesia, analgesia, early ambulation, and a shorter hospital stay. Through various adjuvants like opioids, steroids, magnesium,alpha 2 agonists , etc.have been used in peripheral nerve blocks for many years, the quest for a newer adjuvant for nerve blocks continues. With good knowledge of dermatomes, myotomes and osteotomes of lower limb and the use of ultrasound for precise perineural deposition of local anaesthetics, there is an increase in the success rate with prolonged duration and decrease in the incidence of complications associated with peripheral nerve blocks. The effectiveness of two additives used in the popliteal nerve block for below knee surgery to prolong the duration and effectiveness of anaesthesia has been examined individually by multiple studies and have suggested that additives may have a positive effect on peripheral nerve blocks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients belonging to ASA physical status I and II.
- •Patients posted from orthopedics and general surgery specialties for elective below knee surgeries.
- •Patients willing to give informed consent form.
排除标准
- •Patients with a history of anaphylaxis to local anaesthetics and/or opioids and the study drugs to be used.
- •Patients with a history of drug abuse and psychiatric disease.
- •Morbidly obese patients of BMI greater than 35 kg per meter square.
结局指标
主要结局
To assess, compare and evaluate the onset and duration of sensory and motor blockade, and duration of postoperative analgesia with hemodynamic parameters.
时间窗: 5 minutes,10 minutes,15 minutes, 20 minutes, 25 minutes, 30 minutes, 40 minutes, 50 minutes, 1 hour, 1.5 hours, 2 hours, 2.5 hours, 3 hours, 3.5 hours, and 4 hours
次要结局
- Safety of the procedure & intervetnion(15 minutes, 30 minutes, 1 hour, 2 hours ,4 hours, 6 hours, 8 hours, 12 hours, 16 hours, 20 hours & 24 hours)
研究者
Dr Aditya Hirguppe Somashekhar
BGS Global Institute of Medical Sciences