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Studying the role of probiotics for the treatment of early stage of cervical cancer in Bangladesh

Phase 4
Conditions
Health Condition 1: N870- Mild cervical dysplasia
Registration Number
CTRI/2021/07/034616
Lead Sponsor
BANBEIS Ministry of Education
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Applicable
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Female

Age: 18 -45 years

Non-pregnant

Willing to take conservative treatment and colposcopy (if required)

Not taking antibiotics, probiotics, vitamins and other medications for any other co morbidity within one month before participating in this research work.

Women irrespective of their ethnicity, parity, phase in their cycle and use of contraception, Smoking, alcohol consumption habits.

Women with a diagnosis of LSIL on their latest PAP smear

Women with a first as well as with a repeat LSIL diagnosis

Exclusion Criteria

Age: female below 18 years and above 45 years

Pregnant

Not willing to take conservative treatment and colposcopy (if required)

Taking antibiotics, probiotics, vitamins and other medications for any other co morbidity within one month before participating in this research work.

Women with a previous history of cervical treatment

Women with HIV or hepatitis B/C positive with autoimmune diseases

Patients suffering from invasive cervical cancer

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
absence or decrease the severity of clinical signs-symptoms.Timepoint: Day 0, day 180
Secondary Outcome Measures
NameTimeMethod
The change in vaginal microbiotia (composition, abundance and diversity). <br/ ><br>Lactobacillus level of all groups <br/ ><br>Detection of HPV of patients <br/ ><br>adverse eventsTimepoint: Day 0 and Day 180
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