Effect of Diabetes-specific Formulas on Glucose Metabolism and GLP-1 Secretion in Patients With Type 2 Diabetes
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 25
- 主要终点
- Glucose area under the curve 0-240 minutes
研究概览
简要总结
Diabetes-specific nutritional formulas (DSNFs) are frequently used as part of medical nutrition therapy for patients with type 2 diabetes in order to improve glycemic control and enhance weight reduction. The mechanism through which DSNFs improve postprandial (PP) plasma glucose is not yet known.
The aim of this study is to compare the effects of 2 DSNFs versus oatmeal on PP plasma glucose, serum insulin and serum active glucagon-like peptide-1 (GLP-1), serum free fatty acids (FFA) and serum triglycerides (TG).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with type 2 diabetes treated with oral diabetes medications
排除标准
- •Type 1 diabetes
研究组 & 干预措施
Oatmeal breakfast
consuming 200 kcal of plain cooked oatmeal for breakfast
干预措施: Ultra Glucose Control formula (Dietary Supplement)
Oatmeal breakfast
consuming 200 kcal of plain cooked oatmeal for breakfast
干预措施: Oatmeal breakfast (Dietary Supplement)
Oatmeal breakfast
consuming 200 kcal of plain cooked oatmeal for breakfast
干预措施: Glucerna formula (Dietary Supplement)
Glucerna formula
consuming 200 kcal of Glucerna shake for breakfast
干预措施: Oatmeal breakfast (Dietary Supplement)
Glucerna formula
consuming 200 kcal of Glucerna shake for breakfast
干预措施: Glucerna formula (Dietary Supplement)
Glucerna formula
consuming 200 kcal of Glucerna shake for breakfast
干预措施: Ultra Glucose Control formula (Dietary Supplement)
Ultra Glucose Control formula
consuming 200 kcal of Ultra Glucose Control shake for breakfast
干预措施: Oatmeal breakfast (Dietary Supplement)
Ultra Glucose Control formula
consuming 200 kcal of Ultra Glucose Control shake for breakfast
干预措施: Glucerna formula (Dietary Supplement)
Ultra Glucose Control formula
consuming 200 kcal of Ultra Glucose Control shake for breakfast
干预措施: Ultra Glucose Control formula (Dietary Supplement)
结局指标
主要结局
Glucose area under the curve 0-240 minutes
时间窗: 240 minutes
次要结局
未报告次要终点