Association Between Resuscitation Orders and Mortality in ICU Patients
Active, not recruiting
- Conditions
- Critical Illness
- Interventions
- Other: Resuscitation orders
- Registration Number
- NCT06373068
- Lead Sponsor
- Karolinska Institutet
- Brief Summary
The hypothesis of the study is that a resuscitation order other than full code is associated with increased mortality among critically ill patients. By incorporating conventional variables associated with death such as age, sex, and Simplified Acute Physiological Score, as well as including the new Clinical Frailty Scale in a statistical model, the aim is to investigate whether there is still an increased risk of death that remains unexplained.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 1500
Inclusion Criteria
- Admitted to ICU
Exclusion Criteria
- Second or subsequent admission to ICU during the study period.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Full code Resuscitation orders Patients without any restrictions on the types of treatments available, such as cardiopulmonary resuscitation, intubation, various life support measures, surgery, etc., if indicated. Simple Do-Not-Attempt-Resuscitation Resuscitation orders The only treatment limitation in patient care is cardiopulmonary resuscitation in case of a cardiac arrest. All other indicated devices or treatments may still be utilized. Do not attempt resuscitation with limited scope Resuscitation orders The treatment limitation in patient care includes not performing cardiopulmonary resuscitation and also involve additional limitations, typically including various life support measures.
- Primary Outcome Measures
Name Time Method Mortality 365 days Hazard ratio of death
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Karolinska Institute
🇸🇪Stockholm, Sweden