Association Between Resuscitation Orders and Mortality in ICU Patients

Active, not recruiting

• Conditions: Critical Illness

• Registration Number: NCT06373068
• Lead Sponsor: Karolinska Institutet

Brief Summary

The hypothesis of the study is that a resuscitation order other than full code is associated with increased mortality among critically ill patients. By incorporating conventional variables associated with death such as age, sex, and Simplified Acute Physiological Score, as well as including the new Clinical Frailty Scale in a statistical model, the aim is to investigate whether there is still an increased risk of death that remains unexplained.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-04-15
• Study First Submitted QC: 2024-04-15
• Study First Posted: 2024-04-18
• Study Start: 2024-05-01
• Primary Completion: 2025-02-28
• Status Verified: 2025-05
• Last Update Submitted: 2025-05-02
• Last Update Posted: 2025-05-06
• Study Completion: 2025-06

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 1500

Inclusion Criteria

• Admitted to ICU

Exclusion Criteria

• Second or subsequent admission to ICU during the study period.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mortality	365 days	Hazard ratio of death

Trial Locations

Locations (1)

Karolinska Institute; 🇸🇪 Stockholm, Sweden