Assessment of Cognitive Function in patients with extracranial and intracranial stenosis
Phase 3
- Conditions
- Nervous System Diseases
- Registration Number
- PACTR201911798073249
- Lead Sponsor
- Ain Shams University Hospitals
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Other
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
a) Patients with intracranial/extracraniial stenosis diagnosed by MRA/CTA or DSA, with or without history of stroke or TIA.
b) Their ages are above 18 years old.
Exclusion Criteria
a) Patients suffering any other causes of dementia than vascular dementia
b)Patients suffering heart failure, respiratory failure, renal failure or liver cell failure ( metabolic causes of cognitive decline )
c) Patients with concomitant neurologic disorder potentially affecting cognitive function
d)Patients with enduring mental illness.
e) Patients with hemispheric stroke attributed to middle cerebral artery occlusion
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method improvement of prognosis and cognitive function or at least stopping the deterioration in cognitive function resulting from either intracranial or extracranial stenosis
- Secondary Outcome Measures
Name Time Method Balloon angioplasty and stent insertion plus medical therapy is superior to medical therapy alone