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临床试验/NCT04601090
NCT04601090已完成不适用

Survival Rates and Long-term Outcomes for Patients With COVID-19 Admitted to Norwegian ICUs

Oslo University Hospital1 个研究点 分布在 1 个国家目标入组 860 人开始时间: 2020年9月16日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
860
试验地点
1
主要终点
ICU Survival rate

研究概览

简要总结

The study 'Survival rates and long-term outcomes for patients with COVID-19 admitted to Norwegian ICUs' is a national observational study, including patients admitted to a Norwegian ICU between March 2020 and March 2021. The study will describe survival rates, clinical characteristics and health challenges experienced by survivors the first year after ICU admission caused by COVID-19 disease.

详细描述

The study 'Survival rates and long-term outcomes for patients with COVID-19 admitted to Norwegian ICUS' has two different aims. The first aim is to synthesis data from a National register (Norwegian Intensive care register-NIR) on all COVID-19 patients in Norway admitted to an ICU. These results are of great public interest for many reasons. First of all, it will give us information on the severity of this novel virus, but also how the health care system has coped in treating the severe cases that was admitted to an ICU. The results will potentially be compared to other patient populations with viral pneumonia, but most interestingly to survival rates from other countries. In addition, the data will give us a description on how the distribution of severe cases of COVID-19 have been within Norway (e.g., gender, age, health regions etc.) The second aim of this study is to measure and describe health related challenges COVID-19 patients may experience during their first year from ICU admission. The health-related domains that will be investigated will capture both mental, physical and cognitive health. Knowledge from other patient population admitted to an ICU with acute respiratory failure, indicates that these are the main domains that negatively affect the activity of daily living. Physical, mental and cognitive health challenges will be investigated for the Norwegian COVID -19 population admitted to ICU, and will give important insight to the impact COVID-19 can have on survivors of severe cases, as well as the need for rehabilitation.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients registered in Norwegian Intensive Care Register, that are ≥ 18 years with confirmed cases of COVID-19.

排除标准

  • Exclusion criteria only for follow-up study: Do not understand Norwegian.

结局指标

主要结局

ICU Survival rate

时间窗: up to 30 days

Time to survival

Change in Functional Status

时间窗: 6 and 12 months after ICU admission

Measured by self-reporting using Lawton Instrumental activity of daily living. Higher score indicates better function, and ranges from 0-8.

次要结局

  • Change in Anxiety and Depression(Measured 6 and 12 months after ICU admission)
  • Change in Quality of Life 6 and 12 months after ICU admission(Measured 6 and 12 months after ICU admission)
  • Changes in Cognitive Status(Measured at 6 and 12 months after ICU admission)

研究者

发起方
Oslo University Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Kristin Hofsø

PhD

Oslo University Hospital

研究点 (1)

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