Axonal misrouting in obstetric brachial plexus lesions

Completed

• Conditions: Erb's palsy; OBPL; 10010335

• Registration Number: NL-OMON33209
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 12 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

Patients:
Obstetric brachial plexus lesion

Exclusion Criteria

Patients and controls:
No other disorder affecting the EMG signal recordings at the following levels:
- muscles (example: polymyositis)
- neuro-muscular (example: myastenia gravis)
- peripheral nerves (example: advanced DM)
- CNS (example: CVA)
Patients:
Neurosurgical reconstruction

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>In Experiment 1:<br /><br>CMAP (compound muscle action potential) amplitudes<br /><br>arm function and more specifically muscle strength (MRC (Medical Research<br /><br>Council) scale).<br /><br>In Experiment 2:<br /><br>presence or absence of CMAP or SNAP (sensory nerve action potential)</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>not applicable</p><br>