Comparisons of the Impact of Duloxetine Versus Imipramine on Therapeutic Efficacy, Psychological Distress, Sexual Function, Urethral and Bladder Wall Structure and Blood Flow in Women With Stress Urinary Incontinence: a Randomized Controlled Study
试验速览
- 阶段
- 3 期
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- the score of International Consultation on Incontinence Questionnaire-Urinary Incontinence
研究概览
简要总结
To assess the impact of Duloxetine and Imipramine on therapeutic efficacy, psychological distress, sexual function, bladder wall structure and blood flow in women
详细描述
To assess the impact of Duloxetine and Imipramine on therapeutic efficacy, psychological distress, sexual function, bladder wall structure and blood flow in women
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 25 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Stress urinary incontinence
排除标准
- •Take monoamine oxidase
- •Myocardial infarction critical,cardiovascular insufficiency (such as room blocking, arrhythmia, blood-soaked heart failure, myocardial infarction, stroke and excessive heartbeat).
- •Allergy to duloxetine or imipramine
- •Uncontrolled angular glaucoma patients
- •Pregnant women
研究组 & 干预措施
Duloxetine
Receive Duloxetine 30 mg treatment per day
干预措施: Duloxetine (Drug)
Imipramine
Receive Imipramine 25 mg treatment per day
干预措施: Imipramine (Drug)
结局指标
主要结局
the score of International Consultation on Incontinence Questionnaire-Urinary Incontinence
时间窗: 8 weeks
Between-group difference in the score of International Consultation on Incontinence Questionnaire-Urinary Incontinence
次要结局
- the score of Urgency Severity Scale(8 weeks)
研究者
Sheng-Mou Hsiao
Chief of Department of Obstetrics & Gynecology
Far Eastern Memorial Hospital