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临床试验/TCTR20210421004
TCTR20210421004尚未招募3 期

Efficacy of Optimal dose of Regional Citrate Anticoagulation versus saline flushing in preventing blood circuit clot for intermittent hemodialysis ; A Prospective Randomized Clinical Trial

Bhumibol Adulyadej Hospital0 个研究点目标入组 30 人开始时间: 2021年4月21日最近更新:
适应症

试验速览

阶段
3 期
状态
尚未招募
入组人数
30

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 Years 至 100 Years(—)
性别
All

入选标准

  • Acute setting ; AKI,ESRD
  • Age > 18 yrs
  • Informed consent
  • Undergoing central venous catheters or AVF/AVG, by prescription HD: Low flux dialyzer
  • BFR 200 ml/min
  • Dialyzate Ca 1.75 mEq/L
  • Duration 4 hr

排除标准

  • 1.Patients were treated withantiplatelet,oral anticoagulant therapyorotherdrugs known to affect coagulation within 7 days
  • 2. Acute liver failure
  • 4. Contraindication to systemicanticoagulation:
  • Abnormal plasmatotal calcium <7.0 mg/dL
  • Abnormal plasmatotal magnesium <1.8 mg/dL
  • Abnormal plasmatotal sodium >145 mg/dL
  • metabolic alkalosis; serum bicarb > 28 mEq/L
  • Known allergy to citrate
  • Documented arrhythmia

研究者

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