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Clinical Trials/NCT06546228
NCT06546228
Completed
N/A

Long Term Predictors of Acute Myocardial Infarction in Patients With Coronary Revascularization: a Machine Learning Analysis After a 7 Years Follow-up

Azienda Ospedaliera Universitaria Policlinico "G. Martino"1 site in 1 country652 target enrollmentJanuary 13, 2021

Overview

Phase
N/A
Intervention
Not specified
Conditions
Acute Myocardial Infarction
Sponsor
Azienda Ospedaliera Universitaria Policlinico "G. Martino"
Enrollment
652
Locations
1
Primary Endpoint
Incidence of Acute Myocardial Infarction (AMI)
Status
Completed
Last Updated
last year

Overview

Brief Summary

Worldwide, Ischemic heart disease is the single most common fatal disease. One of the most common causes of acute myocardial infarction is represented by obesity. Numerous cardio metabolic variables play a key role in incidence of adverse cardiovascular outcomes. The purpose of this research was to investigate the factors allowing to acute coronary syndrome, related to the metabolic status, to help guide each patient toward early preventing behaviors.

Registry
clinicaltrials.gov
Start Date
January 13, 2021
End Date
December 31, 2022
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Patients met the criteria for Acute Coronary Syndrome (ACS) as defined by the Joint European Society of Cardiology/American College of Cardiology Committee.
  • Patients underwent immediate coronary revascularization (primary PCI) for ST-Elevation Myocardial Infarction (STEMI).
  • Patients underwent coronary revascularization (early PCI) within 24 hours for Non-ST-Elevation Myocardial Infarction (NSTEMI).
  • Patients underwent diagnostic coronary angiography following coronary artery bypass graft surgery (CABG).

Exclusion Criteria

  • Known coronary artery disease or previous ACS.
  • PCI following CABG.
  • Cardiogenic shock.
  • Atrial fibrillation.
  • Peripheral artery disease.
  • Severe cardiac valve disease.
  • Prosthetic aorta.

Outcomes

Primary Outcomes

Incidence of Acute Myocardial Infarction (AMI)

Time Frame: 7 years

Occurrence of AMI. Unit of measure: Medical records, electrocardiogram (ECG), cardiac biomarkers

Secondary Outcomes

  • Change in Left Ventricular Ejection Fraction (LVEF)(7 years)
  • Incidence of Cardiovascular Death(7 years)

Study Sites (1)

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