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Clinical Trials/NCT03788421
NCT03788421
Completed
Not Applicable

Comparison Between 2 Techniques for Bilateral Salpingectomy During Cesarean Section

Rambam Health Care Campus1 site in 1 country51 target enrollmentJanuary 1, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Sterility, Female
Sponsor
Rambam Health Care Campus
Enrollment
51
Locations
1
Primary Endpoint
Total salpingectomy time.
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

A comparison between 2 techniques for bilateral salpingectomy during cesarean section.

Primary outcomes are total operative time and bilateral completion of the randomized procedure. Secondary outcomes included surgical complications and post operation complications.

Detailed Description

Ovarian cancer is the most lethal gynecologic malignancy. Major contributors to this high mortality are the lack of effective screening strategies, diagnosis at advanced stage of presentation as well as the high risk of recurrence. In the last years the Gynecologic Associations worldwide have recommended that total salpingectomy be considered for potential ovarian cancer risk reduction in benign gynecologic surgeries after completion of childbearing. However, the data are limit regarding the Preferred surgical technique during cesarean section. In this randomized controled trial the investigators will compare between various techniques for bilateral salpingectomy during cesarean section. Primary outcomes are total operative time and bilateral completion of the randomized procedure. Secondary outcomes included surgical complications and post operation complications.

Registry
clinicaltrials.gov
Start Date
January 1, 2019
End Date
September 1, 2021
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Yaniv Zipori MD

Principal Investigator

Rambam Health Care Campus

Eligibility Criteria

Inclusion Criteria

  • Participants undergoing elective Cesarean Section and are interested and have signed informed consent regarding bilateral salpingectomy.

Exclusion Criteria

  • Inability to give informed consent.
  • Preterm delivery (\< 37 weeks' gestation).
  • Fetal demise.
  • Prenatal diagnosis of fetal or placental abnormalities.
  • Previous tubal surgery.
  • The use of anticoagulants.
  • Associated immunosuppressive conditions.

Outcomes

Primary Outcomes

Total salpingectomy time.

Time Frame: Up to 1 week from recruitment

Time in minutes from beginning of salpingectomy procedure until end of the salpingectomy procedure.

Secondary Outcomes

  • Visual analogue score(Up to 2 weeks from surgery)
  • Bleeding during cesarean section(Up to 4 hours from the beginning of the procedure)
  • Need for opioids(Up to 2 weeks from surgery)
  • Hemoglobin level(Up to 5 days from surgery)
  • Postoperative stay(Up to 2 weeks from surgery)
  • Blood transfusion rate(Up to 5 days from surgery)
  • Bleeding during salpingectomy(Up to 4 hours from the beginning of the procedure)
  • Wound complications(Up to 2 weeks from surgery)

Study Sites (1)

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