Heart Transplant Myocardial Fibrosis Study

Phase 4

• Conditions: Diastolic dysfunction; Myocardial fibrosis after heart transplantation; Cardiovascular - Other cardiovascular diseases

• Registration Number: ACTRN12606000193572
• Lead Sponsor: The Alfred Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2006-05-24
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

More than 12 months after heart transplantation. Left ventricular diastolic dysfunction, LVEF > 50%.

Exclusion Criteria

Allergy to or previous therapy with spironolactone.Abnormal left ventricular systolic function, LVEF < 50% or regional wall motion abnormality.Pregnancy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Myocardial function[After 6 months]

Secondary Outcome Measures

Name	Time	Method
Myocardial fibrosis[After 6 months]