Impact of HPV Vaccine On The Prevalence Of Human Papillomavirus In Mouth And Vagina In Norway
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 315
- 试验地点
- 1
- 主要终点
- Vaginal and oral HPV-6, HPV-11, HPV-16 and HPV-18 prevalence
研究概览
简要总结
The overall aim of the study is to assess the effect of school-based Human Papillomavirus (HPV) vaccination by comparing type-specific HPV prevalence between vaccinated and non-vaccinated women born in 1997. Women born in 1997, residence to Norway in 2009 (the year of vaccine initiation of the 1997-cohort) are invited to participate in the study.
详细描述
This cohort is amongst the first that was offered HPV vaccine in an organized vaccination programme globally. The women will be recruited through Facebook ads. The study will enable us to measure differences in the prevalence of HPV types in vagina and the mouth between vaccinated and non-vaccinated young women in Norway.
The womens vaccination status will be validated by linkage to the Norwegian Immunisation Registry (SYSVAK) and their residence status will be validated through linkage to the Norwegian Population Registry.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 20 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Born in 1997
- •Resident of Norway in 2009
排除标准
- •Born before or after 1997
- •Non-resident of Norway in 2009
结局指标
主要结局
Vaginal and oral HPV-6, HPV-11, HPV-16 and HPV-18 prevalence
时间窗: Within 2 months after self-collection of specimens
The differences in HPV types prevalence among vaccinees and non-vaccinees. HPV types will be assessed individually and combined.
次要结局
- Description of oral and vaginal overall genotype distribution among vaccinated and non-vaccination participants(Within 2 months after self-collection of specimens)
研究者
Espen Enerly
Dr Scient
Oslo University Hospital