IRCT20180802040678N4RecruitingPhase 3
Evaluation of the effects of Losartan in patients with corona virus disease 2019
Conditions
Trial Snapshot
- Phase
- Phase 3
- Status
- Recruiting
- Enrollment
- 100
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 years to no limit (—)
- Sex
- All
Inclusion Criteria
- •Laboratory (RT-PCR of oropharyngeal swab) confirmed COVID-19
- •Stable hemodynamic condition
- •Blood pressure =130/85 mmHg
Exclusion Criteria
- •Patient's critical condition
- •Cough exacerbation after initiating Losartan
- •Increasing blood potassium levels or high baseline potassium levels
- •Shock or decreasing blood pressure = 90/60 mmHg after Losartan initiating
- •Acute hepatic failure
- •Acute renal failure
- •Bilateral renal artery stenosis
- •History of uncontrolled hypertension
- •Pregnancy and lactation
- •History of treatment with ACE inhibitors and ARB inhibitors
- •Treatment with phenobarbital, rifampin and fluconazole
Investigators
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