Melatonin Versus Hydroxizin for Pre Operative Anxiety in Elderly Patients With Hip Fracture
Overview
- Phase
- Not Applicable
- Intervention
- Melatonin 5 MG Sublingual Tablet
- Conditions
- Preoperative Anxiety
- Sponsor
- Mongi Slim Hospital
- Enrollment
- 50
- Primary Endpoint
- preoperative anxiety
- Last Updated
- 4 years ago
Overview
Brief Summary
prospective randomized trial including adukt patients scheduled for hip fracture surgery, Randomization into 2 groups: Group A: Hydroxizin peroperatively Group B: Melatonin pre operatively
Detailed Description
prospective randomized trial including adukt patients scheduled for hip fracture surgery, Randomization into 2 groups: Group A: Hydroxizin peroperatively Group B: Melatonin pre operatively Non inclusion criteria: patients with severe cognitive impairement Primary outcome pre operative anxiety assessed with Amsterdam preoperative anxiety and information scale
Investigators
Mhamed Sami Mebazaa
Professor head of anesthesia and intensive care department
Mongi Slim Hospital
Eligibility Criteria
Inclusion Criteria
- •All adult patients scheduled for hip fracture surgery
Exclusion Criteria
- •Patients with contraindications for hydroxizine or Melatonin Patients with severe cognitive impairement
Arms & Interventions
Group A
patients of this group will receive 5 mg of Melatonin 12 hours and 5 mg 2 hours prior to surgery
Intervention: Melatonin 5 MG Sublingual Tablet
Group B
patients of this group will receive 1 mg/kg of Hydroxizin 12 hours and 1 mg/ kg 2 hours prior to surgery
Intervention: Hydroxyzine
Outcomes
Primary Outcomes
preoperative anxiety
Time Frame: 1 hour before surgery
preoperative anxiety scale