Comparing treatment efficacy between recombinant FSH LH and recombinant FSH Highly purified human menopausal gonadotropins(HMG) A Prospective randomized controlled study.
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 390
- 试验地点
- 1
- 主要终点
- Quality of oocytes assessed on the day of oocyte pick up
研究概览
简要总结
HMG injeections and recombinant injections are used in the process of invitro fertilisation. in our study we strive to study whether giving a combination of recombinant FSH and recombinant LH improves the quality of oocytes and improves clinical pregnancy rate. To validate the paramount significance of rLH in influencing key aspects such as follicular development, oocyte and embryo quality, pregnancy and implantation rates
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 22.00 Year(s) 至 44.00 Year(s)（—）
- 性别
- Female
入选标准
- •BMI 18-35 kg/m 2 Unexplained subfertility Male Factor subfertility.
排除标准
- •Oocyte donor patients Congenital uterine anomalies uncorrected septum Patient with endometriosis grade3&4 SOAT, Necrozoospermia.
结局指标
主要结局
Quality of oocytes assessed on the day of oocyte pick up
时间窗: Following 10-11 days of stimulation, once the follicle reaches more than 18 mm, trigger injection is given to induce ovualtion and maturation of follicles. oocyte pickup done 35 hours after trigger injection. after oocyte pickup, following denudation quality of oocytesis assessed on the same day.
次要结局
- Oocyte maturity rate, ICSI normal fertilization(rate, Blastocyst development rate, Clinical Pregnancy)
研究者
Archana S
A4 Hospital and Fertility centre