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Clinical Trials/NCT01825187
NCT01825187
Completed
Not Applicable

Prospective Randomized Controlled Trial Comparing Resident Performance and Clinical Outcomes With Two Different Polypropylene Meshes for Laparoscopic Inguinal Hernias

South East Area Health Education Center, Wilmington, NC1 site in 1 country75 target enrollmentJune 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Hernia, Inguinal
Sponsor
South East Area Health Education Center, Wilmington, NC
Enrollment
75
Locations
1
Primary Endpoint
Inguinal Hernia Mesh Insertion Times
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The purpose of this research study is to measure the clinical effectiveness of two different polypropylene meshes used for laparoscopic inguinal hernias by evaluating subjects' length of hospital stay, perioperative complications, recurrence rate, pain score, comfort level and postoperative quality of life. A secondary goal of the study is to evaluate the ease of use and time it takes surgical residents to place the mesh and perform the surgery using these two different meshes.

Detailed Description

Inguinal hernia repair is one of the most common operations performed by general surgeons in the world. There are two main ways to repair an inguinal hernia, open or laparoscopic. Open compared to laparoscopic, is more invasive and leads to more scarring and longer recovery periods. Laparoscopic repair is done by making a small cut in or just below the umbilicus and has become an accepted standard for inguinal hernia repair and has become the technique of choice for recurrent inguinal hernias. During laparoscopic repair, the placement of a prosthetic mesh aids in reinforcing the abdominal wall and allowing for tension free repair. Meshes also helps to lower the recurrence rate. The most safe and effective type of mesh prosthesis currently being used in laparoscopic inguinal hernia repairs are polypropylene meshes. There is some emerging evidence that "lighter weight" forms of polypropylene meshes may improve quality of life outcomes following surgery for inguinal hernias. Further evaluation is needed to support this evidence.

Registry
clinicaltrials.gov
Start Date
June 2014
End Date
August 31, 2020
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
South East Area Health Education Center, Wilmington, NC
Responsible Party
Principal Investigator
Principal Investigator

William Hope

Director of Surgical Education/Assistant Professor of Surgery

South East Area Health Education Center, Wilmington, NC

Eligibility Criteria

Inclusion Criteria

  • Subjects undergoing laparoscopic repair for the treatment of either single or bilateral inguinal hernias
  • All surgical residents at New Hanover Regional Medical Center

Exclusion Criteria

  • Subjects requiring emergency surgery
  • Pregnant subjects
  • Subjects under the age of 18 years of age

Outcomes

Primary Outcomes

Inguinal Hernia Mesh Insertion Times

Time Frame: During the procedure an average of an hour

The primary outcome measure was a comparison of mesh insertion times and were tested using a 2 × 2 ANOVA on the ranked times. Timing of the mesh placement was documented, which included time from mesh insertion in the trocar until completion of mesh fixation. Laparoscopic fixation was performed by placing four tacks; two in the pubic bone, one medial, and one lateral on the upper portion of the mesh. The types of tacks used were AbsorbaTack™ (Medtronics), sutures, CapSure™ (CR Bard) and OptiFix™ (CR Bard). Timing of mesh placement in robotic repairs included mesh placement and the time to place three suture fixation points; one at the pubis, one at the anterior, and 1 at the lateral abdominal wall at the top of the mesh.

Secondary Outcomes

  • NASA TLX Survey Index Scores(During procedure an average of 1 hour)

Study Sites (1)

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