Guided Bone Regeneration Using Ti-Reinforced PTFE Membrane Vs. Khoury's Technique in Augmentation of Posterior Mandibular Defects
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- Cone Beam Volumetric Topography (CBVT)
研究概览
简要总结
The aim of the present clinical trial is to compare two different alveolar ridge bone augmentation techniques for mandibular horizontal bone defects.
详细描述
Will using PTFE membrane with a mixture of xenograft and particulate autogenous bone result in bone gain similar to standard Khoury's bone shell technique?
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Have one or more missing teeth in the posterior mandibular segment.
- •The alveolar ridge in the edentulous site of the selected patients will have a buccolingual width of less than 5 mm.
- •Sufficient vertical bone height above inferior alveolar nerve.
- •Free of any local or systemic condition that may contraindicate ridge expansion procedure.
- •No sex predilection.
- •The patient will be between the ages of 18-70 years.
排除标准
- •Patients taking any medication that may interfere with bone healing or bone biology.
- •Patients with any systemic disease that may affect bone healing.
- •Any patients with any previous bone grafting procedure at the site of interest.
- •Heavy Smokers (more than 20 cigarettes daily).
- •Patient's that have been diagnosed with periodontal disease, as sufficient ridge height would be improbable.
研究组 & 干预措施
Khoury's bone shell technique
Bone blocks will be harvested from the retromolar area after measuring of the size required and measuring of the donor site anatomy. Piezoelectric device will be used to perform the graft osteotomy. The block size should be slightly larger than the defect size. Sharp bony edges will be smoothened, and the donor defect will be packed with gelatin sponges. The bone block margins will be smoothened and separated into two thinner bone shells using titanium disk with copious saline irrigation. The blocks will be fixed into the recipient site buccally using at least two micro-screws leaving a gap to be filled with bone graft.
干预措施: Khoury's bone shell technique (Procedure)
GBR using Ti-reinforced PTFE Membrane
A non-resorbable ti-enforced polytetrafluoroethylene (PTFE) membrane will be fixed with titanium screws on the lingual bone plate and on the buccal bone plate allowing for packing of particulate mix of bone graft (50% Xenograft: 50% Autogenous graft).
干预措施: GBR using Ti-reinforced PTFE Membrane (Procedure)
结局指标
主要结局
Cone Beam Volumetric Topography (CBVT)
时间窗: 6 Months
次要结局
- Clinical measurement: the frequency of complications(6 Months)
研究者
Ahmed Hassan El-Zaher
Principal Investigator
British University In Egypt