How does heart disease affect cognition and brain structural integrityin diabetes?

Not Applicable

Recruiting

• Conditions: Dementia; Diabetes; Left ventricular hypertrophy; Neurological - Dementias; Metabolic and Endocrine - Diabetes; Cardiovascular - Other cardiovascular diseases

• Registration Number: ACTRN12616000546459
• Lead Sponsor: The Florey Institute of Neuroscience and Mental Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-04-28
• Last Update Posted: 13 July 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 168

Inclusion Criteria

1. Diagnosed with type 2 diabetes
2. Aged over 50 years
3. Able to attend 2 study sessions 2 years apart
4. Have no prior neurological or psychiatric disease, including stroke or dementia
5. Can give informed consent and participate in cognitive testing and MRI scans.

Exclusion Criteria

1. Known prior stroke or dementia
2. Significant medical co-morbidities making survival for 24 months unlikely
3. Normal exclusion criteria for MRI, e.g. pacemaker, implanted metal, severe claustrophobia
4. Severe diabetic nephropathy, eGFR<30

Study & Design

• Study Type: Observational
• Study Design: Not specified