Randomized Clinical Trial of Robot-Assisted Intelligent Rehabilitation Treatment in Comparison With Standard Treatment for Methamphetamine Use Disorders and Alcohol Use Disorders
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- Changes of galvanic skin response during the virtual reality based addiction assessment system
Study Overview
Brief Summary
The purpose of this research is to evaluate the efficacy and safety of Robot-assisted rehabilitation intelligent system as a virtual stand-alone treatment, delivered with minimal clinical monitoring compared with treatment as usual in methamphetamine (MA) use disorders.
Detailed Description
Based on artificial intelligence technology, face recognition technology, virtual reality technology to develop an available Robot-assisted rehabilitation intelligent system. Then, using this intelligent system as a new way of Psychotherapy to provide treatment for methamphetamine patients, and compare it with traditional treatment to verify the efficacy and safety of Robot-assisted rehabilitation intelligent system in Chinese methamphetamine patients.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Care Provider)
Eligibility Criteria
- Ages
- 18 Years to 45 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •In accordance with the Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5) for methamphetamine (MA) use disorders;
- •Education level equal or more than 9 years;
- •Have normal or corrected-to-normal vision;
- •Have normal or corrected-to-normal hearing;
- •Less than 3 months before last drug use;
Exclusion Criteria
- •Current substance use (except nicotine or caffeine);
- •History of disease which influence cognition，such as seizure disorder、cerebrovascular disease、head injury or other severe medication conditions;
- •Intelligence quotient less than 70.
Arms & Interventions
robot-assisted rehabilitation intelligent treatment
Participants assigned to this condition were offered 10 weekly individual sessions of robot-assisted rehabilitation treatment, delivered by the Robot-assisted rehabilitation intelligent system. The system contains 10 core cognitive-behavioral therapy (CBT) skill topics (such as functional analysis, coping skills training, reviewing practice exercises, explaining CBT concepts). A robot therapist demonstrates the target CBT skills and assigns homework to participants.
Intervention: robot-assisted rehabilitation intelligent treatment (Device)
treatment as usual
Participants in the treatment-as-usual group were offered standard treatment at the compulsory isolated detoxification centers and non-compulsory isolated detoxification institutions, which consisted of weekly group and/or individual therapy, as determined by the clinical team.
Intervention: standard psychotherapy treatment (Other)
Outcomes
Primary Outcomes
Changes of galvanic skin response during the virtual reality based addiction assessment system
Time Frame: in 1 year
The galvanic skin response is an emotional physiological indicator, and its unit is ohm.
Secondary Outcomes
- Treatment motivation(in 1 year)
- Reaction inhibition ability(in 1 year)
- Attentional bias related to drugs and emotional stimulation(in 1 year)
- Risky decision-making(in 1 year)
- Anxiety(in 1 year)
- Depression(in 1 year)
- Changes of electroencephalogram power spectrum during the virtual reality based addiction(in 1 year)