The Effect of Exposure to Maternal Human Milk Odor on Physiological State of Preterms.

• Conditions: Health Preterm Infants With no Active Disease; Human Milk Nutrition; Incubator Stay
• Interventions: Other: adding pad with maternal milk in hte incubator

• Registration Number: NCT01012505
• Lead Sponsor: Sheba Medical Center

Brief Summary

Mammalian fetal sensory development comes in an invariant series, with the tactile/kinesthetic and chemosensory systems the earliest functioning and responsive to stimulation, implicating the importance of these foundational sensory systems for later development. Olfaction is essential for neonatal behavioral adaptation in many mammals, including humans. Experiments show that newborns recognize, and are soothed by, the smell of amniotic fluid. Provision of the mother's smell with breast pads, handkerchiefs she has worn, breast milk on a cotton ball or cotton applicator, or other means of providing odor and taste input can facilitate recognition by the infant's mother at a later time and does not appear to be detrimental to the stability of the infant.

Provision of the odor and taste of the mother's milk has been shown to facilitate the infant's mouthing, sucking, arousal, and calming from irritability, especially in preparation for oral feeding. Using 24 hour monitor analysis and cortisol saliva measurements, we will provide quantitive analysis to the effect of smell.

Detailed Description

Not available

Study Timeline

• Status Verified: 2009-11
• Study First Submitted: 2009-11-11
• Study First Submitted QC: 2009-11-12
• Last Update Submitted: 2009-11-12
• Study First Posted: 2009-11-13
• Last Update Posted: 2009-11-13
• Study Start: 2009-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• preterm infants at least 1 week of age
• no active disease or treatment (like respiratory support)
• place in incubator

Exclusion Criteria

• active disease or treatment

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
20 preterm infants	adding pad with maternal milk in hte incubator	20 preterm infants without active disease

Trial Locations

Locations (1)

Sheba medical center; 🇮🇱 Ramat - Gan, Israel