Cross-sectional Study of Chinese Liver Cancer Patients
- Conditions
- Liver Cancer
- Registration Number
- NCT05872828
- Lead Sponsor
- The Nethersole School of Nursing
- Brief Summary
The goal of this cross-sectional study is to investigate the prevalence and risk factors of anxiety and depression and their relationships with immune functions and quality of life among liver cancer patients in the COVID-19 pandemic era. The objectives of this study are:
1. To examine the prevalence of anxiety and depression among patients with liver cancer during the COVID-19 pandemic.
2. To identify risk factors associated with anxiety and depression among these patients.
3. To determine the association between anxiety, depression, immune function, and quality of life among liver cancer patients.
Participants will be asked to fill a digital questionnaire.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ENROLLING_BY_INVITATION
- Sex
- All
- Target Recruitment
- 120
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Anxiety score Baseline Participants' anxiety status with HADS
Depression score Baseline Participants' depression status with HADS
- Secondary Outcome Measures
Name Time Method Quality of life score (The EORTC QLQ-C30) Baseline The European Organization for Research and Treatment of Cancer(EORTC) Quality of Life Questionnaire results. Scores range from 0 to 100. A higher score represents a higher ("better") level of functioning, or a higher ("worse") level of symptoms.
Immune variables 3 Baseline Total lymphocyte count. Collected from daily medical records.
Immune variables 6 Baseline Percentage of lymphocytes. Collected from daily medical records.
Quality of life score (The EORTC QLQ-HCC18) Baseline The Hepatocellular Carcinoma Module of The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire. Scores range from 0 to 100. A higher score represents a high level of symptomatology or problems.
Immune variables 1 Baseline White blood cell counts (WBC). Collected from daily medical records.
Immune variables 2 Baseline Total neutrophil count. Collected from daily medical records.
Immune variables 4 Baseline Total monocyte count. Collected from daily medical records.
Immune variables 5 Baseline Neutrophilic granulocyte percentage. Collected from daily medical records.
Immune variables 7 Baseline Monocyte percentage. Collected from daily medical records.
Immune variables 8 Baseline C-reactive protein (CRP). Collected from daily medical records.
Trial Locations
- Locations (1)
Zhuhai People's Hospital
🇨🇳Zhuhai, Guangdong, China