NCT01034618CompletedNot Applicable
The Additional Effects of Protein Hydrolysate Supplementation on Glucose Homeostasis in Type 2 Diabetes
Conditions
Interventions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Locations
- 1
- Primary Endpoint
- Glucose and insulin homeostasis.
Study Overview
Brief Summary
The insulinotropic effects of protein hydrolysate/amino acid ingestion have been shown to regulate blood glucose homeostasis in both type 2 diabetes patients and normoglycemic controls. The objective of the study is to investigate the optimal dose of such an insulinotropic mixture.
Study Design
- Study Type
- Interventional
- Intervention Model
- Crossover
- Primary Purpose
- Basic Science
- Masking
- Double (Participant, Investigator)
Eligibility Criteria
- Ages
- 40 Years to 70 Years (Adult, Older Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Age between 40 and 70 years
- •Oral blood glucose lowering medication
- •BMI < 35 kg/m2
Exclusion Criteria
- •Exogenous insulin use
- •Cardiac disease (any cardiac event in the last 5 years)
- •Diabetic complications (microvascular complications, microalbuminuria: albumin:creatinine ratio >2,5)
Arms & Interventions
Placebo
Placebo Comparator
Intervention: Protein hydrolyzation (Dietary Supplement)
Intact protein
Experimental
Intervention: Protein hydrolyzation (Dietary Supplement)
Protein hydrolysate
Experimental
Intervention: Protein hydrolyzation (Dietary Supplement)
Outcomes
Primary Outcomes
Glucose and insulin homeostasis.
Secondary Outcomes
- Plasma amino acid profiles
Investigators
Study Sites (1)
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