NCT03479099已完成不适用
Clinical Utility of Combined CTC and ctDNA Assay in the Diagnosis of Primary Lung Cancer
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 111
- 试验地点
- 1
- 主要终点
- Diagnostic sensitivity of combined CTC and ctDNA
研究概览
简要总结
The purpose of this study is to assess clinical utility of combined circulating tumor cell (CTC) and circulating tumor DNA (ctDNA) in the diagnosis of primary lung cancer.
详细描述
The peripheral blood and tumor tissue samples are collected from the participants.CTC and ctDNA are analyzed from the blood samples.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with histology-proven lung cancer or a clinical suspicion of lung cancer
- •Age >=18, < 80 years
- •No previous history of cancer treatment within 5 years
- •Patients who agree to participate
排除标准
- •Patients who have been diagnosed with malignancy within 5 years
- •Patients with previous history of lung cancer
- •Patients who have uncontrolled coagulopathy
结局指标
主要结局
Diagnostic sensitivity of combined CTC and ctDNA
时间窗: 1 year
To compared the sensitivity of combined CTC and ctDNA with those of CTC and ctDNA alone in diagnosis of primary lung cancer
次要结局
- Diagnostic accuracy of combined CTC and ctDNA(1 year)
- Diagnostic specificity of CTC and ctDNA(1 year)
研究者
Sang-Won Um
Associate Professor
Samsung Medical Center
研究点 (1)
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