Automated Imaging Differentiation of Parkinsonism
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 315
- 试验地点
- 21
- 主要终点
- Predicted diagnosis accuracy
研究概览
简要总结
The purpose of this study is to test the performance of the AID-P across 21 sites in the Parkinson Study Group. Each site will perform imaging, clinical scales, diagnosis, and will upload the data to the web-based software tool. The clinical diagnosis will be blinded to the diagnostic algorithm and the imaging diagnosis will be compared to the movement disorders trained neurologist diagnosis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 40 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Parkinson's disease diagnosis within 5-9 years of baseline date
- •MSAp diagnosis
- •PSP diagnosis
排除标准
- •metal implants in the body that preclude an MRI (pacemaker, metallic clip, neurostimulator, etc)
- •claustrophobia
- •pregnancy
研究组 & 干预措施
Parkinson's disease
Clinically diagnosed Parkinson's disease
干预措施: AIDP (Diagnostic Test)
Multiple System Atrophy, Parkinsonian variant
Clinically diagnosed Multiple System Atrophy, Parkinsonian variant
干预措施: AIDP (Diagnostic Test)
Progressive Supranuclear Palsy
Clinically diagnosed Progressive Supranuclear Palsy
干预措施: AIDP (Diagnostic Test)
结局指标
主要结局
Predicted diagnosis accuracy
时间窗: 12-18 months
utilizing the automated imaging differentiation of Parkinsonism (AIDP) tool to predict diagnosis compared to the expertise of two movement disorder specialists
次要结局
未报告次要终点