Deep Learning for the Discrimination Among Bacterial, Fungal, Viral, Amebic and Noninfectious Keratitis: a Nationwide Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10,369
- 试验地点
- 2
- 主要终点
- Area under the receiver operating characteristic curve of the deep learning system
研究概览
简要总结
Detecting the cause of keratitis fast is the premise of providing targeted therapy for reducing vision loss and preventing severe complications. Due to overlapping inflammatory features, even expert cornea specialists have relatively poor performance in the identification of causative pathogen of infectious keraitis. In this project, the investigators aim to develop an automated and accurate deep learning system to discriminate among bacterial, fungal, viral, amebic and noninfectious keratitis based on slit-lamp images and evaluated this system using the datasets obtained from mutiple independent clinical centers across China.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Other
入排标准
- 年龄范围
- 1 Week 至 100 Years(Child, Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Slit-lamp images with sufficient diagnostic certainty and showing keratitis at the active phase.
排除标准
- •Poor-quality images
- •Images presenting mixed infections (i.e., cornea infected by two or more causative pathogens)
结局指标
主要结局
Area under the receiver operating characteristic curve of the deep learning system
时间窗: 2020-2022
次要结局
- Sensitivity of the deep learning system(2020-2022)
- Accuracy of the deep learning system(2020-2022)
- Specificity of the deep learning system(2020-2022)
