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临床试验/NCT05538793
NCT05538793已完成不适用

Deep Learning for the Discrimination Among Bacterial, Fungal, Viral, Amebic and Noninfectious Keratitis: a Nationwide Study

Ningbo Eye Hospital2 个研究点 分布在 1 个国家目标入组 10,369 人开始时间: 2020年7月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
10,369
试验地点
2
主要终点
Area under the receiver operating characteristic curve of the deep learning system

研究概览

简要总结

Detecting the cause of keratitis fast is the premise of providing targeted therapy for reducing vision loss and preventing severe complications. Due to overlapping inflammatory features, even expert cornea specialists have relatively poor performance in the identification of causative pathogen of infectious keraitis. In this project, the investigators aim to develop an automated and accurate deep learning system to discriminate among bacterial, fungal, viral, amebic and noninfectious keratitis based on slit-lamp images and evaluated this system using the datasets obtained from mutiple independent clinical centers across China.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Other

入排标准

年龄范围
1 Week 至 100 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Slit-lamp images with sufficient diagnostic certainty and showing keratitis at the active phase.

排除标准

  • •Poor-quality images
  • •Images presenting mixed infections (i.e., cornea infected by two or more causative pathogens)

结局指标

主要结局

Area under the receiver operating characteristic curve of the deep learning system

时间窗: 2020-2022

次要结局

  • Sensitivity of the deep learning system(2020-2022)
  • Accuracy of the deep learning system(2020-2022)
  • Specificity of the deep learning system(2020-2022)

研究者

发起方
Ningbo Eye Hospital
申办方类型
Other
责任方
Sponsor

研究点 (2)

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