ELDAPT: Elderly with locally advanced Lung cancer: Deciding through geriatric Assessment on the oPtimal Treatment strategy
Recruiting
- Conditions
- geriatricLung cancer1003866610029107
- Registration Number
- NL-OMON54768
- Lead Sponsor
- ederlandse Vereniging van artsen voor Longziekten en Tuberculose
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 288
Inclusion Criteria
Patients with any subtype of NSCLC, primary UICC Stage III, age >= 75 years.
Exclusion Criteria
- No NSCLC
- Primary UICC stage is not III
- younger than 75 years
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Quality-adjusted survival (QAS) </p><br>
- Secondary Outcome Measures
Name Time Method <p>• To perform geriatric assessment in stage III NSCLC patients to select<br /><br>patients fit enough to undergo intensified treatment<br /><br>• To identify reliable elements of the geriatric assessment that are predictive<br /><br>for treatment tolerance and QAS in elderly patients with stage III NSCLC<br /><br>• To determine the predictive value of saliva biomarkers with respect to<br /><br>treatment tolerance and QAS in elderly patients with stage III NSCLCTo develop<br /><br>and validate a clinically applicable geriatric screening instrument that<br /><br>enables appropriate treatment stratification in the elderly NSCLC patient<br /><br>• To compare different treatment strategies in fit elderly patients with<br /><br>respect to<br /><br>o Overall survival<br /><br>o Quality adjusted survival<br /><br>• To compare cost-effectiveness of different treatment strategies for fit<br /><br>elderly patients with stage III NSCLC </p><br>