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Clinical Trials/NCT03502460
NCT03502460
Completed
Not Applicable

Fluid Administration Limited by Lung Ultrasonography in the Operating Room: Correlation to Stroke Volume Variation (ORFALU)

Centre Hospitalier Universitaire, Amiens1 site in 1 country200 target enrollmentMay 31, 2018
ConditionsSurgery

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Surgery
Sponsor
Centre Hospitalier Universitaire, Amiens
Enrollment
200
Locations
1
Primary Endpoint
Apparition of Lines B at Lung Ultrasonography
Status
Completed
Last Updated
7 months ago

Overview

Brief Summary

The possibility of exploring the lungs by lung ultrasound, a non-invasive tool, is becoming increasingly popular for anesthesiologists. Recently, Lichtenstein has described the FALLS protocol (Fluid Administration Limited by Lung Sonography) which uses the potential of pulmonary ultrasound to evaluate early pulmonary overload due to fluid administration at a subclinical stage. Indeed, fluid administration can generate a sub-clinical interstitial syndrome that can be detected by passing from a profile A to a profile B in lung ultrasound. The transition from a profile A to a profile B therefore corresponds to the transition from a state of preload dependent to a state of preload independence. However, this tool has not been studied in the operating room. The main objective of this study will be to study the correlation between pulmonary ultrasound and SV variation measured by esophageal Doppler during fluid administration in patients with haemodynamic optimisation in the operating room during digestive, urological, gynecological and orthopedic surgeries. The main expected result is the following: good correlation between the absence of increased SV in the esophageal Doppler and the appearance of a B-profile lung ultrasound fluid administration in the operating room.

Registry
clinicaltrials.gov
Start Date
May 31, 2018
End Date
October 30, 2019
Last Updated
7 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age ≥ 18 ans
  • inclusion criteria:
  • Patient having a digestive, urological, gynecological, vascular or orthopedic surgery
  • Haemodynamic optimisation requiring titration of the fluid administration
  • Informed consent signed

Exclusion Criteria

  • Non-consent
  • Chronic pulmonary pathology: COPD with pulmonary emphysema, pulmonary fibrosis

Outcomes

Primary Outcomes

Apparition of Lines B at Lung Ultrasonography

Time Frame: 1 day

Study Sites (1)

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