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Clinical Trials/NCT05853562
NCT05853562
Completed
Not Applicable

Effects of Structured Exercise Program on Severity of Dizziness, Kinesiophobia, Balance, Fatigue, Quality of Sleep, Activities of Daily Living and Quality Of Life in Bilateral Vestibular Hypofunction

Miray Budak1 site in 1 country20 target enrollmentSeptember 1, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Bilateral Vestibular Hypofunction
Sponsor
Miray Budak
Enrollment
20
Locations
1
Primary Endpoint
Pittsburgh Sleep Quality Index
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Background: The vestibular rehabilitation is an exercise-based method, aiming to maximize central nervous system(CNS) compensation at vestibular nuclear and other CNS levels for vestibular pathology. A minimal number of studies have documented the impact of Vestibular rehabilitation on the recovery rate of patients with Bilateral Vestibular Hypofunction(BVH).

Objective: The purpose of this study was to investigate the effectiveness of structured vestibular rehabilitation (VR) programs on severity of dizziness, kinesiophobia, balance, fatigue, quality of sleep, activities of daily living( ADL) and quality of life(QoL) in subjects with chronic BVH.

Method: Twenty-five participants diagnosed with BVH were included in the study. A structured VR program was applied in 50-minute sessions once a week and as a home exercise program 3 days a week over 8 weeks. Participants were evaluated for severity of dizziness with the Visual Analog Scale (VAS), for kinesiophobia with the Tampa Scale of Kinesiophobia (TSK), for balance with the Semitandem, tandem, and standing tests, for quality of sleep with the Pittsburgh Sleep Quality Index (PSQI), for ADL with the Vestibular Disorders Activities of Daily Life (VADL), for QoL with Dizziness Handicap Inventory (DHI) and for fatigue with the Fatigue Severity Scale (FSS) at the baseline (T0), at 4th week (T1), 8th week (T2), and 20th week (T3) after study started.

Registry
clinicaltrials.gov
Start Date
September 1, 2021
End Date
May 31, 2022
Last Updated
2 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Miray Budak
Responsible Party
Sponsor Investigator
Principal Investigator

Miray Budak

Asst Prof.

Istanbul Medipol University Hospital

Eligibility Criteria

Inclusion Criteria

  • Being between 20-80 years old
  • Diagnosed with bilateral peripheral vestibular hypofunction by videonystagmography
  • Have symptoms for more than three months from onset of illness

Exclusion Criteria

  • having no symptoms of bilateral peripheral vestibular hypofunction
  • having Meniere's disease, vestibular migraine and other undulating vestibular disorders, cognitive, visual, neurological or general motor impairment
  • having previously received vestibular rehabilitation

Outcomes

Primary Outcomes

Pittsburgh Sleep Quality Index

Time Frame: Change from Baseline Systolic Blood Pressure at 4 / 8 / 12 / 16 weeks

It is a self-rated questionnaire which assesses sleep quality and disturbances over a 1-month time interval. The seven component scores consist of subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbances, use of sleeping medication, and daytime dysfunction. Each scored 0 (no difficulty) to 3 (severe difficulty). The component scores are summed to produce a global score (range 0 to 21). Higher scores indicate worse sleep quality

Visual Analog Scale

Time Frame: Change from Baseline Systolic Blood Pressure at 4 / 8 / 12 / 16 weeks

It is a validated, subjective scale used to measure the intensity or frequency of various symptoms. Scores are based on self-reported measures of symptoms that are recorded with a single handwritten mark placed at one point along the length of a 10-cm line that represents a continuum between the two ends of the scale-"no symptom" on the left end (0 cm) of the scale and the "worst symptom" on the right end of the scale (10 cm). We used this scale to measure the severity of dizziness

Tampa Scale of Kinesiophobia

Time Frame: Change from Baseline Systolic Blood Pressure at 4 / 8 / 12 / 16 weeks

It is a 17 items self-reporting questionnaire based on evaluation of fear of movement, fear of physical activity, and fear avoidance. The total score of the scale ranges from 17- 68, where 17 means no kinesiophobia, 68 means severe kinesiophobia, and score ± 37 indicates there is kinesiophobia

Semitandem, Tandem, and Standing tests

Time Frame: Change from Baseline Systolic Blood Pressure at 4 / 8 / 12 / 16 weeks

Semitandem, Tandem, and Standing tests were used to evaluate balance. Semitandem test 30 , Tandem test 30 , Standing tests 30 Equilibrium times (sec) with eyes open-closed were recorded on hard and soft surfaces

Vestibular Disorders Activities of Daily Life

Time Frame: Change from Baseline Systolic Blood Pressure at 4 / 8 / 12 / 16 weeks

This scale is used to determine the degree of independence of patients with vestibular disorders, perceived inadequacies and vestibular complaints in daily activities. The scale consists of 28 items. The subscales are evaluated under three sub-headings as Functional-F- Ambulation-A- and Instrumental-E

Fatigue Severity Scale

Time Frame: Change from Baseline Systolic Blood Pressure at 4 / 8 / 12 / 16 weeks

It was used to assess fatigue. There are 9 questions in the scale and each question consists of 7 points. An increase in the scale score indicates an increase in the level of fatigue. It detects the state of fatigue in the last month

Dizziness Handicap Inventory

Time Frame: Change from Baseline Systolic Blood Pressure at 4 / 8 / 12 / 16 weeks

It is used to assess the impact of dizziness on quality of life. It consists of 25 clauses which determine the aggravating factors associated with dizziness and shakiness and also the emotional and functional results of vestibular system diseases. The inventory consists of 3 sub-dimensions, intended to determine physical, emotional and functional effects of the vestibular system diseases

Study Sites (1)

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