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The Effect of Vaginal Isosorbide Mononitrate Administration on Cervical Ripening before Induction of Labor

Phase 3
Recruiting
Conditions
cervical ripening.
Registration Number
IRCT20191018045150N1
Lead Sponsor
Islamic Azad University of Mashhad
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Female
Target Recruitment
64
Inclusion Criteria

primigravida mother who have gestational age over 40 weeks.
primigravida mother who have singleton pregnancy.
primigravida mother who have fetus in a Cephalic presentation with a Bishop score < 4.

Exclusion Criteria

Full term Primigravida who have Previous scar on the uterus.
Full term Primigravida who have polyhydramnios
Full term Primigravida who have blood pressre> 160/ 110
Full term Primigravida who have proteinuria = 1
Primigravida who have a history of intolerance to isosorbide mononitrate
Primigravida who are candidates for cesarean section

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Bishop score. Timepoint: Bishop's score is measured before the intervention, 12 hours after the first visit, and every 4 hours after the second visit. Method of measurement: bishop score scale.
Secondary Outcome Measures
NameTimeMethod
Mother's blood pressure. Timepoint: Mother's blood pressure is measured before the intervention, 12 hours after the first visit, and every 4 hours after the second visit. Method of measurement: Mercury Barometer.
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