Effects of Whole Body Vibration Training on Bone Health, Physical Fitness, and Neuromotor Performance in Individuals With Subacute Stroke: a Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Level of bone resorption marker CTx
研究概览
简要总结
The overall aim of the proposed study is to determine whether whole body vibration is beneficial in promoting bone turnover, physical fitness and neuromotor performance in patients with subacute stroke.
详细描述
Brief periods of Whole body vibration (WBV) have been shown to improve bone density in post-menopausal women and children with cerebral palsy. In addition to the apparent benefits on bone health, WBV has been shown to increase muscle strength, postural control, muscular blood flow and oxygen uptake in various populations. Therefore, WBV can potentially be used as a tool to improve muscle strength, balance, and cardiovascular performance, especially for those with relatively low level of functioning. Stroke patients are therefore possible beneficiaries of WBV, as they often demonstrate muscle weakness, balance deficits, and poor cardiovascular function, in addition to bone loss. Only one pilot study has examined the effects of WBV in stroke patients. Van Nes et al.showed that postural stability in chronic stroke patients is improved after a few minutes of WBV at 30Hz and 3mm amplitude. The overall aim of the proposed study is to determine whether whole body vibration is beneficial in promoting bone turnover, physical fitness and neuromotor performance in patients with subacute stroke.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnosis of stroke
- •medically stable
- •able to understand simple verbal commands
- •of chinese origin
排除标准
- •previous stroke in addition to the current admission
- •other neurological conditions, in addition to stroke
- •significant musculoskeletal or vascular conditions in the lower extremity
- •metal implants in the lower extremity
- •previous fracture in the lower extremity
- •are taking or were taking bone resorption inhibitors
研究组 & 干预措施
WBV
In their regular physiotherapy sessions, the subjects in the experimental group will receive whole body vibration therapy for a duration of 4 weeks during their stay in the Tung Wah Hospital.
干预措施: Whole body vibration therapy (Device)
CON
The subjects in this group will not receive whole body vibration therapy.
干预措施: standing on the vibration platform but no vibration will be applied (Other)
结局指标
主要结局
Level of bone resorption marker CTx
时间窗: baseline, immediately after treatment, and 2-month follow-up
Level of bone formation marker, BSAP
时间窗: baseline, immediately after treatment, and 2-month follow-up
次要结局
- Six minute walk test(baseline, immediately after treatment, and 2-month follow-up)
- Ankle arm index(baseline, immediately after treatment, and 2-month follow-up)
- Functional Ambulation category(baseline, immediately after treatment, and 2-month follow-up)
- Leg muscle strength (hand-held dynamometry)(baseline, immediately after treatment, and 2-month follow-up)
- Berg Balance Scale(baseline, immediately after treatment, and 2-month follow-up)
- Modified Ashworth Scale of Spasticity(baseline, immediately after treatment, and 2-month follow-up)
- Sensory threshold to light touch in the foot(baseline, immediately after treatment, and 2-month follow-up)
- Fugl-Meyer Motor Assessment(baseline, immediately after treatment, and 2-month follow-up)