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BC-101 in Treatment of Nasolabial Fold Wrinkles

Phase 1
Not yet recruiting
Conditions
Nasolabial Fold Wrinkles
Registration Number
NCT05162326
Lead Sponsor
Bright Cell, Inc.
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Not yet recruiting
Sex
All
Target Recruitment
9
Inclusion Criteria

Inclusion Criteria:<br><br> 1. Subjects who are in general good health condition.<br><br> 2. Subjects who have moderate to extremely deep bilateral nasolabial fold wrinkles, as<br> documented by a score of 3 or greater on the six-point Evaluator Wrinkle Severity<br> Assessment scale (0-5).<br><br> 3. Subjects who are dissatisfied with both nasolabial fold wrinkles based on a score of<br> -1 or -2 on the Subject Wrinkle Assessment Scale (-2 to +2).<br><br> 4. Subjects who voluntarily adhere to the research procedures and ensure good<br> compliance during the research period.<br><br> 5. Subjects who fully understand the research nature of this study and sign the<br> informed consent.<br><br>Exclusion Criteria:<br><br> 1. Subjects who have an active cutaneous infection on the face.<br><br> 2. Subjects with existing malignant neoplasm.<br><br> 3. Subjects with persistent pre-cancerous lesions (e.g., actinic keratosis).<br><br> 4. Subjects who have active dermal diseases, inflammation, or any related disease.<br><br> 5. Subjects who have cosmetic or surgical treatment on nasolabial fold area in 3 months<br> before the study (including laser, chemical peels, fillers, botulinum toxin).<br><br> 6. Subjects who are pregnant, breastfeeding, or whose urinary pregnancy test is<br> positive before participation in the study.<br><br> 7. Subjects who are allergic to low-molecular-weight heparin sodium or human albumin.

Exclusion Criteria

Not provided

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Incidence of any treatment-emergent adverse events
Secondary Outcome Measures
NameTimeMethod
Changes in wrinkle severity assessment from baseline
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