Waterhoudend contrast versus oliehoudend contrast voor het doorspuiten van de eileiders tijdens een baarmoederfoto - de lange termijn effecten.
- Conditions
- Subfertility<br />H2Oil<br />Hysterosalpingography<br />HSG<br />Oil-based contrast medium<br />Water-based contrast medium<br />Tubal patency testing
- Registration Number
- NL-OMON24080
- Lead Sponsor
- VU University Medical Centre Amsterdam
- Brief Summary
Dreyer K, van Rijswijk J, Mijatovic V, et al. Oil-Based or Water-Based Contrast for Hysterosalpingography in Infertile Women. N Engl J Med. 2017; May 25: 376:2043-2052.<br> Kieslinger DC, .. van Rijswijk J et al. Embryo selection using time-lapse analysis (Early Embryo Viability Assessment) in conjunction with standard morphology: a prospective two-center pilot study. Hum Reprod. 2016;31(11):2450-2457.<br> Becker JH, van Rijswijk J et al. Is intrapartum fever associated with ST-waveform changes of the fetal electrocardiogram? A retrospective cohort study. BJOG. 2012;119(11):1410-6.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 1119
Participants of the Water- versus Oil (H2Oil) study who were recruited in 27 hospitals (4 academic, 12 teaching and 11 non-teaching hospitals) in the Netherlands, between February 2012 and October 2014.
Exclusion criteria of the H2Oil study:
1. Endocrino-pathological diseases as: PCOS, Cushing syndrome, adrenal hyperplasia, hyperprolactinemia, acromegaly, hypothalamic amenorrhea, hypothyroidy, diabetes mellitus type 1;
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Ongoing pregnancy rate following HSG.
- Secondary Outcome Measures
Name Time Method Biochemical pregnancy, clinical pregnancy, miscarriage, ectopic pregnancy, multiple pregnancy, time from randomization to ongoing pregnancy, received fertility treatments, mode of conception, complications during pregnancy and delivery, neonatal outcomes, the aim and ability to get a second child, cost calculations of oil based contrast / water based contrast and assisted reproductive technology (ART) treatments.