跳至主要内容
临床试验/EUCTR2008-004830-26-NL
EUCTR2008-004830-26-NL进行中(未招募)不适用

Optimization of electroconvulsive therapy (ECT) and continuation pharmacotherapy in major depressive disorder - ECT optimization

Erasmus MC0 个研究点开始时间: 2009年4月17日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
发起方
Erasmus MC

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

性别
All

入选标准

  • Major depressive disorder (DSM-IV-TR)
  • Hamilton Rating Scale for Depression = 18
  • ECT indication
  • If age = 65 years, first depressive episode before age 65 and Mini Mental State Examination = 24
  • At least 5 days free from medication before start doubble blind medication/ECT
  • Informed consent
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range
  • F.1.3 Elderly (>=65 years) yes
  • F.1.3.1 Number of subjects for this age range

排除标准

  • Alcohol- or drug dependence last 3 months
  • Serious neurologic illness
  • Endocrinologic illness affecting HPA-axis
  • Use of anti-epileptic medication
  • Bipolar disorder, schizoaffective disorder, schizophrenia
  • Contra-indication for nortriptyline
  • Pregnancy or possibility for pregnancy and no adequate contraceptive measures

研究者

发起方
Erasmus MC

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