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临床试验/NCT03292627
NCT03292627已完成不适用

Applying Non-invasive Hemodynamic Monitor to Predict the Risk of Perioperative Hypotension in Geriatric Patients Underwent Endoscopic Invasive Procedure

National Taiwan University Hospital1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2017年10月3日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
200
试验地点
1
主要终点
ICON decrease 40%

研究概览

简要总结

Investigators include the patients who need painless invasive endoscopic procedure, investigators collect the demographic data and apply the non-invasive device ICON on participants during the who procedure.

详细描述

Invasive endoscopy procedure including Endoscopic Retrograde Cholangio-Pancreatography (ERCP), endoscopic ultrasound guided fine needle aspiration (EUS-FNA), Endoscopic Retrograde Biliary Drainage (ERBD) and others is more and more popular which become the standard treatment before surgical intervention. However; the elder group who need this procedure is getting more common. The painless endoscopic sedation for elder group who has more comorbidity is not easy. During the procedure, the investigators found that the anticholinergic medication-buscopam which in order to suppress intestine mobilization can cause obvious tachycardia. Tachycardia makes the stroke volume decrease which enhance the perioperative hypotension, and the vasodilation effect of the analgesics make it worse.

Investigators are trying to find the non-invasive predictor of perioperative hypotension in geriatric group. Investigators collected the patients who need painless endoscopic invasive procedure, investigators will record their hemodynamic data including estimated cardiac output (CCO),index of contractility (ICON),NBP,HR,and saturation. Investigators also add the evaluation of frailty to evaluate the relationship between frailty and perioperative complications.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
50 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patient who need painless endoscopic invasive procedures
  • age above 50 y/o

排除标准

  • 未提供

结局指标

主要结局

ICON decrease 40%

时间窗: during the painless procedure

estimated index of contractility decrease 40%

次要结局

  • perioperative hypotension 40%(during the painless procedure)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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