跳至主要内容
临床试验/CTRI/2024/02/062636
CTRI/2024/02/062636已完成4 期

"Comparative evaluation of efficacy of neem mouthwash versus dexamethasone mouthwash as an adjuvant in the symptomatic management of oral submucous fibrosis: A randomized clinical trial"

POKURU APARNA1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2024年2月23日最近更新:

试验速览

阶段
4 期
状态
已完成
发起方
入组人数
30
试验地点
1
主要终点
THERE WILL BE REDUCTION IN BURNING SENSATION OF MOUTH.

研究概览

简要总结

A total number of 60 patients diagnosed to be having Oral submucous fibrosis were randomly categorized into two groups i.e. Group A and Group B. Each Group consisted of 30 patients. Group A patients were given Neem mouthwash and Group B patients were given  Dexamethasone mouthwash 2 times daily for 1 week. Patients in both the groups were advised to hold the mixture of mouthwash in mouth for 4-5 min and advised to spit out after using it in the mouth as a rinse. Patients were advised for cessation of habits prior to start of treatment regime and was instructed to use the mouthwash for one week and  recalled for follow up after 1 week. The recordings of interincisal mouth opening and burning sensation were recorded pre and post treatment. Intensity of Burning sensation was recorded using Visual analogue scale (VAS) and Inter incisal mouth opening were measured using scale and divider. And the data was recorded and sent to statistical analysis.

研究设计

研究类型
Interventional
分配方式
Other

入排标准

年龄范围
18.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • 1 PATIENTS ABOVE THE AGE OF 18 YEARS CLINICALLY DIAGNOSED WITH ORAL SUBMUCOUS FIBROSIS.
  • 2 PATIENTS WILLING TO PATICIPATE IN THE STUDY.
  • 3 PATIENTS WILLING TO QUIT THE HABIT AS INSTRUCTED.

排除标准

  • 1 PATIENTS WHO ARE ALREADY UNDERGOING TREATMENT FOR ORAL SUBMUCOUS FIBROSIS.
  • 2 PATIENTS WITH TMJ PROBLEMS, PERICORONITIS OF LOWER THIRD MOLARS ETC,WHICH MAY CAUSE REDUCED MOUTH OPENING.
  • 3 PATIENTS WITH PAST HISTORY OF TB.

结局指标

主要结局

THERE WILL BE REDUCTION IN BURNING SENSATION OF MOUTH.

时间窗: 1 week

次要结局

  • THERE WILL BE INCREASE IN INTERINCISAL MOUTH OPENING(1 WEEK)

研究者

发起方
POKURU APARNA
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

POKURU APARNA

NARAYANA DENTAL COLLEGE & HOSPITAL

研究点 (1)

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