A Proof of Principle Study Investigating the Influence of Diclofenac on Perfusion Changes During Cutaneous Negative Pressure Wound Therapy
Phase 4
Completed
- Conditions
- Wonden die behandeld kunnen worden met negatieve druk therapieWounds
- Registration Number
- NL-OMON48444
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 18
Inclusion Criteria
* Between 18-35 years of age
* Informed consent
* Male
Exclusion Criteria
* Nicotine abuse
* Gastro-intestinal complaints
* Diclofenac allergy
* Cardiovascular disease
* Neuropathy
* Skin disease of the forearm
* Use of drugs outside of those relating to the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>8.1.1 Main study parameter/endpoint<br /><br><br /><br>The main study parameter of this experiment will be the mean LDF flux of the<br /><br>last 5 minutes of the 20-minute -200 mm Hg NPWT period of the thee study arms. </p><br>
- Secondary Outcome Measures
Name Time Method