Comparative Study Between the Outcome of Intra-articular Injection of Platelet Rich Plasma Versus Hyaluronic Acid in Arthroscopic Management of Temporomandibular Degenerative Joint Diseases: A Randomized Clinical Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Temporomandibular Joint Disorders
- Sponsor
- Sohag University
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Maximum Interincisal Opening (MIO) Measurements
- Last Updated
- 4 years ago
Overview
Brief Summary
The aim of this study is to evaluate the efficacy of intra-articular injection of platelet rich plasma versus hyaluronic acid following diagnostic arthroscopy in the management of patients suffering from degenerative temporomandibular joint (TMJ).
This is a prospective randomized study of 20 patients with TMJ degenerative joint diseases Wilkes IV, V.
Patients will be divided into two groups; Group A: will be treated with operative arthroscopy plus intra-articular platelet rich plasma.
Group B: will be treated with operative arthroscopy plus intra-articular hyaluronic acid.
Investigators
Ahmad Mohammad Abd-elmoniem
Principal Investigator
Sohag University
Eligibility Criteria
Inclusion Criteria
- •- All patients with reduced mouth opening and/or painful maximum mouth opening.
- •Joint pain.
- •Patients with radiological evidence of degenerative joint disease.
- •Patients with unsuccessful medical conservative treatment for at least two months.
- •Unilateral or bilateral temporomandibular joint involvement.
- •Wilkes stages IV and V
Exclusion Criteria
- •- Patients with bony ankylosis .
- •Patients with advanced resorption of the glenoid fossa.
- •Patients with infection or tumors around joint area
- •Patients unfit for intervention medically.
- •Patients who refused to share in the study
Outcomes
Primary Outcomes
Maximum Interincisal Opening (MIO) Measurements
Time Frame: change from baseline maximum interincisal mouth opening in millimeters at 6 months postoperative
change in maximum inter-incisal mouth opening will be measured in millimeters between preoperative and postoperative at 1 week,3 weeks, the every month till 6 months
Pain Intensity Measurements
Time Frame: change from preoperative pain intensity according to 100 -point visual analogue scale at 6 months postoperative
A 100 -point visual analogue scale (VAS) for the assessment of pain intensity with 0 as the absence of pain and 100 as the worst pain imaginable With filled standardized charts.