PHOENIX - Pre-eclampsia in HOspital: Early iNductIon or eXpectant management

Not Applicable

Completed

Conditions: Pre-eclampsia in women between 34+0 and 36+6 weeks of gestation
Pregnancy and Childbirth
Gestational [pregnancy-induced] hypertension with significant proteinuria

Registration Number: ISRCTN01879376

Lead Sponsor: King's College London

Brief Summary: 2019 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/30691508 protocol (added 31/01/2019) 2019 Results article in https://www.ncbi.nlm.nih.gov/pubmed/31472930 results (added 02/09/2019) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34024312/ Results of PEACOCK nested study of prognostic model (added 25/05/2021) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35861912/ Cost-utility analysis (added 22/07/2022) 2022 Funder report results in https://www.journalslibrary.nihr.ac.uk/hta/published-articles/CWWH0622/#/full-report (added 13/12/2022) 2024 Results article in https://pubmed.ncbi.nlm.nih.gov/38757271/ Secondary analysis of PHOEBE (PHOENIX-3) sub-study data (added 21/05/2024)

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Female

Target Recruitment: 901

Inclusion Criteria

Current inclusion criteria as of 05/10/2016:
1. Women between 34+0 and 36+6 weeks of gestation
2. Confirmed as having pre-eclampsia (as defined as defined by International Society for the Study of Hypertension in Pregnancy {ISSHP} 2014 statement)
3. Singleton or dichorionic diamniotic (DCDA) twin pregnancy
4. Aged 18 years or over at the time of screening
5. Able to give written informed consent

Previous inclusion criteria:
1. Women between 34+0 and 36+6 weeks of gestation
2. Confirmed as having pre-eclampsia (as defined by the NICE guidelines on Hypertension in Pregnancy)
3. An in-patient in a consultant-led maternity unit
4. Singleton or dichorionic diamniotic (DCDA) twin pregnancy
5. Aged 18 years or over at the time of screening
6. Able to give written informed consent

Exclusion Criteria

Women will be excluded from participating in the study if a decision has already been made to delivery within the next 48 hours