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Clinical Trials/ISRCTN13825248
ISRCTN13825248
Completed
Not Applicable

A single blind randomised controlled trial to determine the effectiveness and cost utility of manual chest physiotherapy techniques in the management of infective exacerbations of Chronic Obstructive Pulmonary Disease

niversity of East Anglia (UK)0 sites550 target enrollmentMarch 16, 2005
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ConditionsChronic Obstructive Pulmonary Disease (COPD)RespiratoryChronic obstructive pulmonary disease (COPD)

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Sponsor
niversity of East Anglia (UK)
Enrollment
550
Status
Completed
Last Updated
11 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
March 16, 2005
End Date
TBD
Last Updated
11 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
niversity of East Anglia (UK)

Eligibility Criteria

Inclusion Criteria

  • •Patients admitted to participating hospitals with infective exacerbations of COPD.
  • •Inclusion Criteria:
  • •1\. Diagnosis of COPD as defined by the British Thoracic Society; namely
  • •a. A forced expiratory volume in the first second (FEV1\) of \<80% of the predicted value, which is predominantly irreversible
  • •b. Signs and symptoms of cough, breathlessness and \+/\- wheeze
  • •c. In more severe disease there may be cyanosis and peripheral oedema
  • •2\. An infective exacerbation as set out by the British Thoracic Society; namely
  • •a. A worsening of previous stable condition, a new respiratory event or complication imposed upon established COPD
  • •b. Signs and symptoms of increased wheeze, dyspnoea, sputum volume and purulence, chest tightness and fluid retention

Exclusion Criteria

  • •1\. Cognitive impairment, rendering patients unable to give fully informed consent
  • •2\. Contraindications to the use of manual techniques; namely
  • •a. Osteoporosis
  • •b. Frank haemoptysis
  • •c. Bronchial hyper\-reactivity
  • •d. Known respiratory system malignancy
  • •3\. No evidence of excess sputum production after examination (i.e. the patient does not report excess secretions and no signs of excess secretions on auscultation)

Outcomes

Primary Outcomes

Not specified

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