A single blind randomised controlled trial to determine the effectiveness and cost utility of manual chest physiotherapy techniques in the management of infective exacerbations of Chronic Obstructive Pulmonary Disease

niversity of East Anglia (UK)0 个研究点目标入组 550 人开始时间: 2005年3月16日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•Patients admitted to participating hospitals with infective exacerbations of COPD.
•Inclusion Criteria:
•1. Diagnosis of COPD as defined by the British Thoracic Society; namely
•a. A forced expiratory volume in the first second (FEV1) of <80% of the predicted value, which is predominantly irreversible
•b. Signs and symptoms of cough, breathlessness and +/- wheeze
•c. In more severe disease there may be cyanosis and peripheral oedema
•2. An infective exacerbation as set out by the British Thoracic Society; namely
•a. A worsening of previous stable condition, a new respiratory event or complication imposed upon established COPD
•b. Signs and symptoms of increased wheeze, dyspnoea, sputum volume and purulence, chest tightness and fluid retention

•1. Cognitive impairment, rendering patients unable to give fully informed consent
•2. Contraindications to the use of manual techniques; namely
•a. Osteoporosis
•b. Frank haemoptysis
•c. Bronchial hyper-reactivity
•d. Known respiratory system malignancy
•3. No evidence of excess sputum production after examination (i.e. the patient does not report excess secretions and no signs of excess secretions on auscultation)

发起方

niversity of East Anglia (UK)