JPRN-UMIN000022603
Completed
未知
on-randomized, prospective, non-controlled study of changes of lipid parameters after introduction of evolocumab in patients with heterozygous familial hypercholesterolemia under LDL-apheresis therapy. - Impact of evelocumab in homozygous familial hypercholesterolemia under LDL-apheresis.
ConditionsHomozygous familial hypercholesterolemia
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Homozygous familial hypercholesterolemia
- Sponsor
- Kanazawa University Hospital
- Enrollment
- 2
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •Myocardial infarction or unstable angina within 8 weeks Severe anemia (Hb \<10g/dL) Allergy against evolocumab Immunosupressive therapy Severe hepatic disorder (ASTorALT\>100IU/L) Severe renal disorder (BUN\>40mg/dL or Cre\>2\.0mg/dL) (Possible of) pregnancy
Outcomes
Primary Outcomes
Not specified
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