ISRCTN18135766
Completed
未知
Effectiveness of hypertension management with an amlodipine and perindopril arginine-based strategy in Morocco
SERVIER (Morocco)0 sites1,614 target enrollmentApril 5, 2024
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- SERVIER (Morocco)
- Enrollment
- 1614
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Men or women aged \=18 years who document informed consent.
- •2\. Hypertensive patients previously treated with amlodipine monotherapy, uncontrolled and for whom the treating physician decides to add perindopril arginine.
Exclusion Criteria
- •1\.Age \< 18 years
- •2\.Pregnancy, breastfeeding or possibility of becoming pregnant during the study
- •3\.Current participation in another randomized study or within the previous 3 months
- •4\.Known symptomatic orthostatic hypotension
- •5\.Known hyperkalemia or hypokalemia
- •6\.History of arterial hypertension known to be resistant to the free combination or in a single tablet with perindopril and calcium channel blockers or contraindications to treatment with perindopril or amlodipine
- •7\.Known secondary hypertension or complicated hypertension
- •8\.Known renal insufficiency: patients with a creatinine clearance value classifying them as moderate or severe renal insufficiency according to the national or international classification of chronic renal insufficiency or bilateral stenosis of the renal artery or stenosis at solitary kidney or history of gout
- •9\.Known complicated liver disease
- •10\.Chronic pancreatitis
Outcomes
Primary Outcomes
Not specified
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