Comparing the effects of Atorvastatin and Rosuvastatin in preventing acute kidney injury due to contrast media
- Conditions
- Other and unspecified drugs and medicamentContrast Induced Nephropathy.
- Registration Number
- IRCT2017101236737N1
- Lead Sponsor
- Vice chancellor for research, Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 200
occurrence of first episode of ST elevation Myocardial Infarction (STEMI); performing primary per-cutaneous coronary intervention for patients.
Exclusion criteria: patients under-dialysis; acute kidney injury before angiography; cardiogenic shock; consumption of drugs like N-acetyl cysteine, vitamin C, consumption of venous contrast for other cause, manitol, diuretics, Theophylline and Dopamin in recent two weeks before PCI; having intra-aortic balloon pump; patients with previous cardiac surgery; patients who were candidate for CABG after angioplasty; patients who received G2b3a drugs during PPCI
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method evel of serum creatinine. Timepoint: 24 hours after intervention and 72 hours after intervention. Method of measurement: mg/ deciliter.
- Secondary Outcome Measures
Name Time Method Glumerolar filtration rate. Timepoint: 24hours after intervention and 72hours after intervention. Method of measurement: ml/min/1.73 m2.