Artificial Intelligence for Screening of Multiple Corneal Diseases

Recruiting

• Conditions: Deep Learning; Corneal Disease; Screening
• Interventions: Diagnostic Test: Cornea diseases diagnosed by artificial intelligence algorithm

• Registration Number: NCT06211218
• Lead Sponsor: Tianjin Eye Hospital

Brief Summary

This study developed a deep learning algorithm based on anterior segment images and prospectively validated its ability to identify corneal diseases.The effectiveness and accuracy of this algorithm was evaluated by sensitivity, specificity, positive predictive value, negative predictive value, and area under curve.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-12-06
• Primary Completion: 2021-12-06
• Study First Submitted: 2024-01-08
• Study First Submitted QC: 2024-01-08
• Study First Posted: 2024-01-18
• Status Verified: 2024-10
• Last Update Submitted: 2024-10-31
• Last Update Posted: 2024-11-04
• Study Completion: 2024-12-06

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 3000

Inclusion Criteria

1. The quality of slit-lamp images should clinical acceptable.
2. More than 90% of the slit-lamp image area including three main regions (sclera, pupil, and lens) are easy to read and discriminate.

Exclusion Criteria

1）Insufficient information for diagnosis.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Cornea diseases diagnosed by artificial intelligence algorithm	Cornea diseases diagnosed by artificial intelligence algorithm	-

Primary Outcome Measures

Name	Time	Method
Area under curve	1 week	We used the receiver operating characteristic (ROC) curve and area under curve to examine the ability of this artificial intelligence algorism recognition and classification of corneal diseases.
Sensitivity and specificity	1 week	We used sensitivity and specificity to examine the ability of this artificial intelligence algorism recognition and classification of corneal diseases.

Trial Locations

Locations (1)

Tiajin Eye Hospital; 🇨🇳 Tianjin, Tianjin, China