Clinical study on the effect of Qingfei Huayu Tongfu recipe on regulating alveolar epithelial-mesenchymal transition in mechanically ventilated patients with sepsis-related ARDS

Jiangsu Provincial Hospital of Traditional Chinese Medicine0 个研究点开始时间: 待定最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•1. Those who meet the diagnostic criteria for sepsis and ARDS and the TCM syndrome differentiation criteria of blood stasis and heat congesting the lungs and viscera-qi obstruction.
•2. Aged between 18 and 80 years old, regardless of gender.
•3. Acute onset, duration of disease within 2 days.
•4. Give informed consent and volunteer to be tested. The process of obtaining informed consent should comply with GCP regulations.

•1. Already participated in other clinical trials.
•2. Pregnancy or lactation.
•3. Cancer patients with disseminated tumors or receiving chemotherapy and other special treatments.
•4. Severe liver function abnormalities (TBIL = 171 µmmol/L or daily increase = 17.1 µmmol/L).
•5. Severe renal dysfunction (Scr increases by more than 26.5 µmmol/L or 1.5 times the baseline value within 48 hours, or urine output is <0.5 ml/kg/h, lasting for more than 6 hours).
•6. Unstable angina/acute myocardial infarction, heart rate <50 beats/min, second degree or above conduction block;
•7. Use of 2 vasoactive drugs within 2 hours before the start of the study and the systolic blood pressure is still <90mmHg.
•8. For gastrointestinal dysfunction, traditional Chinese medicine cannot be administered through the gastrointestinal tract.
•9. Those who are allergic to Chinese medicine or intolerant to Chinese medicine.

发起方

Jiangsu Provincial Hospital of Traditional Chinese Medicine