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Clinical Trials/CTRI/2025/04/085558
CTRI/2025/04/085558Not yet recruitingPhase 4

To assess the effect of Prapaundarikadi taila nasya in the management of Khalitya- Acontrolled Clinical study

KLE Academy of Higher Education and Research Center1 site in 1 country20 target enrollmentStarted: May 20, 2025Last updated:

Trial Snapshot

Phase
Phase 4
Status
Not yet recruiting
Sponsor
Enrollment
20
Locations
1
Primary Endpoint
To assess the effect of Prapaundarikadi Thailam Nasya in the management of ‘Khalitya’

Study Overview

Brief Summary

Review of literature

Khalitya is mentions in several ancient Ayurvedic texts. It has been included in Shiroroga by

Acharya Charaka and Ashtanga Hridayakar, indicating its classification within diseases of the

head and scalp. This classification is based on the location of the disease and its

etiopathogenesis.

According to Ashtanghridaya, nine diseases occurring on the outer part of the head over the scalp

are categorized as shiroroga, among which Khalitya finds its place. Additionally, other classical

Ayurvedic texts such as Sushrut Samhita, Ashtangasamgrah, Yoga Ratnakar, and Madhav Nidan

have also included Khalitya under kshudra roga, or minor diseases.

This categorization in kshudra roga is attributed to the mildness of Khalitya compared to other

major diseases. While Khalitya may not pose life-threatening risks, its impact on physical

appearance and mental well-being can still be significant, underscoring the importance of

understanding and addressing this condition within the broader context of Ayurvedic medicine.

Khalitya, according to Ayurveda, is primarily considered a Pitta-dominant Tridoshjanya Vyadhi.

This classification suggests that it involves an imbalance of all three doshas—Vata, Pitta, and

Kapha—along with the involvement of Rakta dosha.

In this context, vitiated Pitta, specifically Bhrajaka Pitta, plays a significant role. When it

becomes aggravated or imbalanced, it can lead to weakening of the hair from the roots. This

weakening can result in hair fall and other related issues.

Additionally, the involvement of vitiated Vata worsens the condition by further weakening the

hair roots. Vata dosha, when imbalanced, is known to disrupt the natural stability and

nourishment of the hair follicles, making them more susceptible to damage and loss.

Moreover, vitiated Kapha, along with Rakta dosha, contributes to Khalitya by obstructing the

hair roots (Romakupa). Kapha dosha, when deranged, can lead to excessive buildup and

congestion, which may impede the nourishment and growth of hair follicles. Rakta dosha, which

represents the blood and its components, can exacerbate this obstruction by causing stagnation or

blockages in the microcirculation around the hair roots.Prapaundarikadi taila is mentioned by

Ashtanga hridya as prathimarsha nasya for shiroroga. The ingerdients of this taila having

properties of Tridosha hara,balya,cakshushya and having rasayana properties.This study aims to

evaluate the effect of i Prapaundarikadi taila nasya in khalitya

Study Design

Study Type
Interventional
Allocation
Other
Masking
Not Applicable

Eligibility Criteria

Ages
16.00 Year(s) to 60.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • individual of both sexes ranging from 16 years to 60 years.
  • individual with symptoms of itchy scalp, hairfall, keeshabhoomi daha, burning and dryness of scalp.

Exclusion Criteria

  • individual less than 16 years and above 60 years, no history of hair loss due to surgery, hereditary, systemic disorder.

Outcomes

Primary Outcomes

To assess the effect of Prapaundarikadi Thailam Nasya in the management of ‘Khalitya’

Time Frame: 10 months

Secondary Outcomes

  • To compare the effect of Prapaundarikadi Thailam Nasya with Shadbindu Tailanasya in(the management of ‘Khalitya’ (Hair fall).)

Investigators

Sponsor
KLE Academy of Higher Education and Research Center
Sponsor Class
Other [Deemed to be University]

Study Sites (1)

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