MedPath

Starling Registry Study

Completed
Conditions
Hemodynamic Monitoring
Interventions
Device: Starling
Registration Number
NCT04648293
Lead Sponsor
Baxter Healthcare Corporation
Brief Summary

Hemodynamic optimization of critically ill patients is a goal for clinicians in order to afford the patient the best possible outcomes. Being able to precisely and rapidly determine patient fluid responsiveness provides the bedside physician and nursing staff the information needed to make critical decisions in regards to the patient's fluid status and management of additional fluids and medications.

As fluid management and cardiac output determination are linked to better decision-making and improved outcomes in ICU, the use of a dynamic assessment of fluid responsiveness becomes a key tool for patient management.

This study is designed to collect treatment and outcome data on patients that have undergone hemodynamic monitoring in a wide variety of clinical settings, involving a variety of patient diagnoses.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1207
Inclusion Criteria
  • ≥18 to 95 years of age
  • Patient has undergone hemodynamic monitoring with the Starling monitor
  • Hemodynamic monitoring was completed no earlier than 2018
Exclusion Criteria
  • None

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
No Improvement in HemodynamicsStarlingOver the course of a patient's hospitalization, data will be collected on patients from the initiation to completion of hemodynamic monitoring with the Starling monitor in a wide variety of clinical settings, and for different diagnoses. No Improvement in hemodynamics is exhibited by no increase in both Cardiac Output and Stroke Volume observed at 12 hour intervals from time of monitoring until completion.
Improvement in HemodynamicsStarlingOver the course of a patient's hospitalization, data will be collected on patients from the initiation to completion of hemodynamic monitoring with the Starling monitor in a wide variety of clinical settings, and for different diagnoses. Improvement in hemodynamics is exhibited by an increase in both Cardiac Output and Stroke Volume observed at 12 hour intervals from time of monitoring until completion.
Primary Outcome Measures
NameTimeMethod
30 day in-hospital mortality rateDay 1 to Day 30
Number of days in HospitalDay 1 to Day 30
Volume of treatment fluid administeredTime of monitoring to completion
Number of days on vasopressorsDay 1 to Day 30
Number of participants needing mechanical ventilationTime of monitoring to completion
Lactate levelTime of monitoring to completion
Number of days in Intensive Care Unit (ICU)Day 1 to Day 30
Secondary Outcome Measures
NameTimeMethod
Number of participants with device related Serious Adverse EventsTime of monitoring to completion
Percent of participants that are fluid responsiveTime of monitoring to completion
Number of participants with COVID-19Time of monitoring to completion
Percent of participants with fluid responsiveness in diastolic dysfunctionTime of monitoring to completion
Number of participants with COVID-19 by treatment typeTime of monitoring to completion
Number of participants with COVID-19 by outcome typeTime of monitoring to completion
Number of participants with diastolic dysfunctionTime of monitoring to completion
Number of participants with device related Non-Serious Adverse EventsTime of monitoring to completion

Trial Locations

Locations (3)

Baxter Investigational Site

🇺🇸

Columbus, Ohio, United States

Mercy Hospital St. Louis

🇺🇸

Saint Louis, Missouri, United States

Baxter Investigational SIte

🇺🇸

Galveston, Texas, United States

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